An energy-restricted Mediterranean diet combined with physical activity helps preserve bone mineral density (BMD) in older women with metabolic syndrome and obesity. The secondary analysis of the PREDIMED-Plus trial including 924 participants aged 55-75 in Spain showed that those following this regimen experienced greater weight loss and increased lumbar spine BMD over three years compared with a control group on a standard Mediterranean diet. The intervention was particularly beneficial for women, showing a significant BMD increase, while no significant effects were observed in men. The study underscores the importance of integrating dietary and physical activity interventions to mitigate age-related bone density decline. The research was supported by Spanish institutions.
The Takeaway: Energy-reduced Mediterranean diet and exercise improve bone health in older women.
Cited from Medscape